B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子1抗體

Name: B淋巴細(xì)胞白血病前體蛋白轉(zhuǎn)錄因子1抗體bs-12296R
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簡(jiǎn)要描述：Pbx 1, 2, 3 and 4 are members of the TALE (three amino acid loop extension) family of homeodomain-containing proteins. Human pre-B cell acute leukemias are frequently associated with a t(1;19)(q23;p13.3) chromosomal rearrangement, which creates a chimeric gene encoding a fusion between the E2A and Pbx 1 gene products. Pbx 2 and Pbx 3 share 92% and 94% respective identities with Pbx 1 over a 266 amino acid region flanking their homeobox domains, while all three proteins are quite divergent a